Yellow fever vaccination is recommended for most of the country, including Rio de Janeiro, Sao Paulo and Iguazu Falls. Malaria tablets are not usually needed.
Vaccines for Brazil
Book this week to give your vaccines time to work.
Some courses can be speeded up. A yellow fever certificate becomes valid 10 days after your vaccine.
Current health alerts
Oropouche virus disease outbreak ongoing. It is spread by midges and mosquitoes and there is no vaccine, so bite avoidance matters, especially in pregnancy.
Advised for most travellers
Advised for some travellers, depending on your trip
TuberculosisTB (BCG) vaccine is advised for unvaccinated children under 16 who will live in the country for more than 3 months, and for some health workers. It is not given in pharmacy; ask your GP.
These are suggestions only and may differ from what our expert clinician advises at your consultation.
Entry rules
There are no certificate requirements under International Health Regulations.
There is a risk of yellow fever in parts of Brazil, so vaccination is about protecting you, not entry rules. Other countries may ask for a certificate when you arrive from Brazil.
Malaria
Low risk. Tablets are not usually advised.
Low risk in the Amazon basin, including the city of Manaus: awareness and bite avoidance.
Very low risk in the rest of Brazil.
No risk at Iguazu Falls.
For travellers at higher risk going to the Amazon basin, atovaquone with proguanil, doxycycline or mefloquine are suitable options.
Other health risks
Zika
There is a risk, with more than 22,000 cases reported in 2025. Pregnant travellers and couples planning a pregnancy should seek advice before booking.
Schistosomiasis
Present in fresh water. Avoid swimming or wading in lakes and rivers.
Methanol poisoning
Cases linked to contaminated alcoholic drinks were reported in 2025, mostly in Sao Paulo state.
Insect-borne infections
Chagas disease and leishmaniasis occur in parts of South America. Avoid bites day and night.
More than one country?
Add each country when you book and we’ll plan for the whole route.
Summarised from NaTHNaC TravelHealthPro, checked 10 November 2026. Advice can change, so we check it again at your appointment.
Can’t see your destination? We still cover it.
We show some of our most popular destinations here, but we give travel vaccine advice for wherever you’re going. Tell us your route when you book, or give us a call.